All measurements need to be relative to some source of known flux. In practice, planets are used because they are among the few astronomical objects sufficiently strong at millimeter wavelengths for which flux density predictions are possible and sufficiently accurate. They are then used as primary calibrators to bootstrap the flux of the stronger quasars which are point sources. Since the quasars are highly variable, a regular monitoring (each month) is needed. These observations require a very good weather with a small amount of precipitable water vapor (< 4 mm) and a stable atmospheric phase. If not properly taken into account, the quasar variability can produce an error in the flux scale during one configuration which does not result in a simple scale factor in the final image, but introduces artifacts.